Journal article
A large infrapatellar fat pad protects against knee pain and lateral tibial cartilage volume loss
AJ Teichtahl, E Wulidasari, SRE Brady, Y Wang, AE Wluka, C Ding, GG Giles, FM Cicuttini
Arthritis Research and Therapy | BMC | Published : 2015
Abstract
Introduction: The infrapatellar fat pad (IPFP) is commonly resected during knee joint arthroplasty, but the ramifications of doing so are unclear. This longitudinal study determined whether the size of the IPFP (maximum cross-sectional area (CSA)) was associated with knee cartilage loss and the development of knee pain in adults without knee osteoarthritis (OA). Methods: A total of 297 adults without American College of Rheumatology clinical criteria for a diagnosis of knee OA were recruited. Knee MRI was performed at baseline and an average of 2.3years later. IPFP maximal CSA and tibial cartilage volume were measured from MRI. A large and small IPFP were defined by the median split, with a ..
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Grants
Awarded by Cancer Council Victoria
Funding Acknowledgements
AJT is the recipient of the NHMRC Early Career Fellowship (#1073284). SREB is supported by an NHMRC Clinical Postgraduate Research scholarship (#1074979). YW and AEW are the recipients of NHMRC Career Development Fellowship (Clinical Level 1 #1065464 and Clinical Level 2 #1063574, respectively). CD is the recipient of Australian Research Council Future Fellowship (Level 2, FT110100276). The Melbourne Collaborative Cohort Study recruitment was funded by VicHealth and The Cancer Council of Victoria. This study was funded by a program grant from the National Health and Medical Research Council (NHMRC; 209057) and was further supported by infrastructure provided by The Cancer Council of Victoria. We would like to acknowledge the NHMRC (Project Grant 334150) and Colonial Foundation for the knee MRI study.